Cristiano Ronaldo became the first player to net 400 goals across Europe's top five leagues.
It wasn't enough on Saturday to maintain Juventus' perfect start to the season.
Ronaldo, who has been accused of rape in a civil lawsuit in the United States, scored in the 1-1 draw against Genoa. It was his fifth Serie A goal in nine matches.
Ronaldo has 311 goals in La Liga for Real Madrid, and 84 in the English Premier League for Manchester United.
Juventus won all of its previous 10 matches across Serie A and the Champions League. However, coach Massimiliano Allegri believes this result will help his side ahead of what is arguably its toughest test yet, Manchester United on Tuesday in Ronaldo's return to Old Trafford.
"We drifted out of the game after a good start to the second half and, instead of making it 2-0, we let them make it 1-1," Allegri said. "This isn't good, because it's with matches like this that titles are lost. After 10 minutes of the second half we were already thinking about Manchester. We needed to have more focus.
Impactful in return
"But it's a draw that serves us well. It'll get our feet back to earth and help us understand that, to win matches, you need sacrifice and hard work."
Ronaldo had last weekend off while Juventus was idle during the international break. Normally the star of his national team, he was left off Portugal's squad.
Ronaldo started brightly: A header came off the crossbar and he drew a save from Genoa goalkeeper Andrei Radu in the opening 14 minutes.
Less than five minutes later, he scored. There was a miscommunication between Radu and his defender on Joao Cancelo's cross from the left, allowing Ronaldo a simple tap-in at the far post.
Genoa's first goal at Juventus since January 2013 came from Daniel Bessa with a header in the 67th minute.
It was a memorable first match back in charge for Ivan Juric, who returned to Genoa for his third spell as coach.